Rongmin Zhao
Assistant Professor
Education:
Ph.D. Chinese Academy of Agricultural Sciences, 1995Department:
Cell & Systems BiologyResearch Areas:
Molecular Biology & Biotechnology, Cell & Developmental Biology, Functional Genomics & Genetics, Plant BiologyGraduate Programs:
Cell & Systems BiologyOffice phone:
416-208-2740Lab phone:
416-208-2741Fax:
416-287-7676Office:
SY 248Lab:
SY 235rzhao (at)utsc [dot] utoronto [dot] ca
Address:
Department of Biological Sciences
University of Toronto at Scarborough
1265 Military Trail
Scarborough, Ontario
M1C 1A4
Research:
My research interests involve understanding the mechanisms of cellular protein homeostasis and the protein quality control systems (PQC) under physiological and stress conditions. Plant Arabidopsis thaliana and yeast Saccharomyces cerevisiae are used as model organisms. Proteomics, biochemical and biophysical approaches are applied to study how molecular chaperones are involved in de novo protein synthesis and protein functions, and the interplay of chaperones and the proteasome in PQC upon protein misfolding.
2009
(2009). Overexpression of AtHSP90.2, AtHSP90.5 and AtHSP90.7 in Arabidopsis thaliana enhances plant sensitivity to salt and drought stresses.
Planta (in press).
2008
(2008). Molecular chaperone Hsp90 stabilizes Pih1/Nop17 to maintain R2TP complex activity that regulates snoRNA accumulation.
The Journal of Cell Biology. 180, 563-578.
2007
(2007). Molecular interaction network of the Hsp90 chaperone system.
Advances in Experimental Medicine and Biology. 594, 27-36.
(2007). Expression of a constitutively activated plasma membrane H+-ATPase alters plant development and increases salt tolerance.
Plant Physiology. 144, 1763-1776.
2006
(2006). Specificity in substrate and cofactor recognition by the N-terminal domain of the chaperone ClpX.
Proceedings of the National Academy of Sciences, USA. 103, 17724-17729.
2005
(2005). Hsp90: a chaperone for protein folding and gene regulation.
Biochemistry and Cell Biology. 83, 703-71.
(2005). Navigating the chaperone network: an integrative map of physical and genetic interactions mediated by the hsp90 chaperone.
Cell. 120, 715-727.
2001
(2001). Expression and characterization of the anion transporter homologue Ynl275wp in yeast Saccharomyces cerevisiae.
American Journal of Physiology -Cell Physiology281. 281, C33-45.
2000
(2000). Cosuppression of a plasma membrane H+-ATPase isoform impairs sucrose translocation, stomatal opening, plant growth, and male fertility..
The Plant Cell. 12, 535-546.