Daphne Goring

D_Goring.jpg
Full Professor
Education: 
PhD, University of Toronto;MSc, McGill University;BSc, Trent University
Department: 
Cell & Systems Biology
Research Areas: 
Plant Biology, Functional Genomics & Genetics, Cell & Developmental Biology
Graduate Programs: 
Cell & Systems Biology
Office phone: 
416-978-2378
Lab phone: 
416-978-8158
Fax: 
416-978-5878
Office: 
ESC 4029
Lab: 
ESC 4027

d [dot] goring (at)utoronto [dot] ca

Address: 

Department of Cell & Systems Biology
University of Toronto
25 Willcocks Street
Toronto, Ontario
Canada M5S 3B2

Research: 

My overall research interests are to understand how plant cells communicate through signal transduction pathways to regulate plant growth and development in Arabidopsis and Brassica (canola).  One area that we investigate is the signalling systems regulating compatible and self-incompatible pollen responses in the pistil.  These are critical recognition systems for selecting which pollen grains will be accepted or rejected, and thus, selecting optimal pollen grains for fertilization.  By studying the molecular and cellular mechanisms of these recognition systems, my research group has identified several new protein players including a receptor kinase, E3 ubiquitin ligase, and the exocyst complex.  Typically, the genes encoding these proteins belong to multi-gene families, and so, we also use functional genomics approaches to characterize these gene families, identify novel plant signalling networks, and determine the biological processes that are regulated by these networks in Arabidopsis.  Finally, we also investigate the biological functions of a novel receptor kinase family, the PERK family, in Arabidopsis.

2010
Chapman, L., Goring, D. (2010).  Pollen-pistil interactions regulating successful fertilization in the Brassicaceae. J Exp Bot. 61, Abstract
Haasen, K.E., Goring, D.R. (2010).  The recognition and rejection of self-incompatible pollen in the Brassicaceae. Botanical Studies . 51, Abstract
Chong, Y.T., Gidda, S.K., Sanford, C., Parkinson, J., Mullen, R.T., Goring, D.R. (2010).  Characterization of the Arabidopsis thaliana exocyst complex gene families by phylogenetic, expression profiling, and subcellular localization studies. New Phytologist. 185, in press. Abstract
2009
Samuel, M.A., Chong, Y.T., Haasen, K.E., Aldea-Brydges, M.G., Stone, S.L., Goring, D.R. (2009).  Cellular Pathways Regulating Responses to Compatible and Self-Incompatible Pollen in Brassica and Arabidopsis Stigmas Intersect at Exo70A1, a Putative Component of the Exocyst Complex. The Plant Cell. 21, 2655-2671. Abstract
Yee, D., Goring, D.R. (2009).  The diversity of plant U-box E3 ubiquitin ligases: from upstream activators to downstream target substrates. Journal of Experimental Botany. 60, 1109-1121. Abstract
2008
Sanabria, N., Goring, D., Nürnberger, T., Dubery, I. (2008).  Self/nonself perception and recognition mechanisms in plants: a comparison of self-incompatibility and innate immunity. New Phytologist. 178, 503-514. Abstract
Samuel, M.A., Yee, D., Haasen, K.E., Goring, D.R. (2008).  ‘Self’ pollen rejection through the intersection of two cellular pathways in the Brassicaceae: Self-incompatibility and the compatible pollen response. Self-Incompatibility in Flowering Plants – Evolution, Diversity, and Mechanisms. 173-191. Abstract
Samuel, M.A., Mudgil, Y., Salt, J.N., Delmas, F., Ramachandran, S., Chilelli, A., Goring, D.R. (2008).  Interactions between the S-Domain Receptor Kinases and AtPUB-ARM E3 Ubiquitin Ligases Suggest a Conserved Signaling Pathway in Arabidopsis. Plant Physiol. 147, 2084-2095. Abstract
2007
Humphrey, T.V., Bonetta, D.T., Goring, D.R. (2007).  Sentinels at the wall: Cell wall receptors and sensors. New Phytologist. 176, 7-21. Abstract
2006
Haffani, Y., Silva-Gagliardi, N., Sewter, S., Aldea, M., Zhao, Z., Nakhamchik, A., Cameron, R., Goring, D. (2006).  Altered Expression of PERK Receptor Kinases in Arabidopsis Leads to Changes in Growth and Floral Organ Formation. Plant Signaling & Behavior. 1(5), 251-260. Abstract
Samuel, M., Salt, J., Shiu, S., Goring, D. (2006).  Multifunctional arm repeat domains in plants. Int Rev Cytol. 253, 01 . Abstract
2004
Haffani, Y., Silva, N., Goring, D. (2004).  Receptor Kinase Signalling in Plants.. Can J Bot. 82, 01 . Abstract
Mudgil, Y., Shiu, S., Stone, S., Salt, J., Goring, D. (2004).  A Large Complement of the Predicted Arabidopsis ARM Repeat Proteins are Members of the U-Box E3 Ubiquitin Ligase Family.. Plant Physiol. 134, 59-66. Abstract
Goring, D., Walker, J. (2004).  Self-rejection, A new kinase connection.. Science. 303, 1474-1475.
Nakhamchik, A., Zhao, Z., Provart, N., Shiu, S., Keatley, S., Cameron, R., Goring, D. (2004).  A Comprehensive Expression Analysis of the Arabidopsis Proline-rich Extensin-like Receptor Kinase Gene Family using Bioinformatic and Experimental Approaches. Plant Cell Physiol. 45(12), 1875-1881. Abstract
2003
Stone, S., Anderson, E., Mullen, R., Goring, D. (2003).  ARC1 is an E3 ubiquitin ligase and promotes the ubiquitination of proteins during the rejection of self-incompatible Brassica pollen.. Plant Cell. 15, 885-898. Abstract
2002
Silva, N., Goring, D. (2002).  The Proline-rich, Extensin-like Receptor Kinase-1 (PERK1) gene is rapidly induced by wounding.. Plant Mol Biol. 50, 667-685. Abstract
2001
Mazzurco, M., Sulaman, W., Elina, H., Cock, J.M., Goring, D.R. (2001).  Identification of a cysteine required for the interaction of two thioredoxin h proteins with the kinase domain of the S locus receptor kinase.. Plant Mol. Biol.. 45, 365-376.
Silva, N.F., Stone, S.L., Christie, L.N., Sulaman, W., Nazarian, K.A.P., Burnett, L.A., Arnoldo, M., Rothstein, S.J., Goring, D.R. (2001).  Expression of the S receptor kinase in self-compatible Brassica napus cv. Westar leads to the allele-specific rejection of self-incompatible Brassica napus pollen.. Mol. Gen. Genet.. 265, 552-559.
1999
Stone, S.L., Arnoldo, M., Goring, D.R. (1999).  A breakdown of Brassica self-incompatibility in ARC1 antisense transgenic plants.. Science. 286, 1729-1731.
1998
Gu, T., Mazzurco, M., Matias, D.D., Sulaman, W., Goring, D.R. (1998).  Binding of a novel arm repeat protein to the kinase domain of the S locus receptor kinase.. Proc. Natl. Acad. Sci. USA. 95, 382-387.
1997
Sulaman, W., Arnoldo, M., Yu, K., Tulsieram, L., Rothstein, S., Goring, D.R. (1997).  Loss of callose in the stigmas papillae does not affect the Brassica self-incompatibility phenotype.. Planta. 203, 327-331.
1996
Bower, M.S., Matias, D.D., Fernandes-Carvalho, E., Mazzurco, M., Gu, T., Rothstein, S., Goring, D.R. (1996).  Two members of the thioredoxin-h family interact with the kinase domain of a Brassica S-locus receptor kinase.. Plant Cell. 8, 1641-1650.