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Thomas Berleth

berleth.jpg
Full Professor
Education: 
Ph.D., University of Tuebingen, 1989.
Department: 
Cell & Systems Biology
Research Areas: 
Cell & Developmental Biology, Functional Genomics & Genetics, Plant Biology
Graduate Programs: 
Cell & Systems Biology, Developmental Biology
Office phone: 
416-946-3734
Lab phone: 
416-946-7441
Fax: 
416-978-5878
URL: 
http://labs.csb.utoronto.ca/berleth
Office: 
ESC 4068
Lab: 
ESC 4066

thomas [dot] berleth (at)utoronto [dot] ca

Address: 

Department of Cell & Systems Biology
University of Toronto
25 Willcocks Street
Toronto, Ontario
Canada M5S 3B2

Research: 

Molecular developmental genetics and genomics. Plant embryo and vascular development. Projects focus on the molecular genetic analysis of signaling pathways involved in embryonic root initiation and vascular tissue formation in the model plant Arabidopsis thaliana and in trees. The strategy is based on the identification of genes by mutation in Arabidopsis, which are subsequently isolated and analyzed at the molecular level. The strategy involves the generation of genomic resources in Arabidopsis, such as transgenic enhancer-trap and activation-tag collections and the transfer of knowledge obtained in Arabidopsis to biotechnological applications in trees.

  • Selected publications:
2007
Vidaurre, D., Ploense, S., Krogan, N., Berleth, T. (2007).  AMP1 and MP antagonistically regulate embryo and meristem development in Arabidopsis.. Development. 134, 2561-2567. Abstract
2006
Scarpella, E., Marcos, D., Friml, J., Berleth, T. (2006).  Control of leaf vascular patterning by polar auxin transport. Genes & Dev.. 20, 1015-1027. Abstract
2004
Hardtke, C., Ckurshumova, W., Vidaurre, D., Singh, S., Stamatiou, G., Tiwari, S., Hagen, G., Guilfoyle, T., Berleth, T. (2004).  Overlapping and non-redundant functions of the Auxin Response Factors MP and NPH4.. Development. 131, 1089-1100.
Scarpella, E., Francis, P., Berleth, T. (2004).  Stage specific markers define early stages of procambium in Arabidopsis leaves and correlate termination of higher-order vein formation with mesophyll differentiation.. Development. 131, 3445-3455. Abstract
Berleth, T., Krogan, N., Scarpella, E. (2004).  Auxin - turning genes on and turning cells around.. Current Opinions in Plant Sciences. 7, 553-563.
lic, K., Berleth, T., Provart, N. (2004).  BlastDigester - a web-based program for efficient CAPS marker design. TRENDS in Genetics . 20(7), 280-283. Abstract
Scarpella, E., Berleth, T. (2004).  Polar Signals in Vascular Development.. IN Polarity in Plants K. Lindsey ed., Blackwell Publishing, Sheffield, U.K.. 264-288.
2003
Mattsson, J., Ckurshumova, W., Berleth, T. (2003).  Auxin signaling in Arabidopsis leaf vascular development.. Plant Physiology. 131, 1327-1339.
2002
Beeckman, T., Przemeck, G.K.H., Stamatiou, G., Lau, R., Terryn, N., De Rycke, R., Inz, D., Berleth, T. (2002).  Genetic complexity of gene function in Arabidopsis embryogenesis.. Plant Physiology. 130, 1883-1893.
Berleth, T., Chatfield, S. (2002).  Embryogenesis: pattern formation from a single cell.. The Arabidopsis Book.
2001
Berleth, T. (2001).  Directionality of signaling in embryo and vascular development.. Journal of Plant Growth Regulation. 20, 14-21.
Berleth, T., Sachs, T. (2001).  Plant morphogenesis: long-distance coordination and local patterning.. Current Opinion in Plant Biology. 4(1), 57-63.
2000
Berleth, T., Mattsson, J. (2000).  Vascular development: tracing signals along veins.. Current Opinion in Plant Biology. 3, 406-411.
Mattsson, J., Sung, R.Z., Berleth, T. (2000).  Grow with the flow.. Current Biology. 10, R91.
Berleth, T. (2000).  Vascular Development: Hidden Networks.. Current Biology. 10, R658-R661.
Berleth, T., Mattsson, J., Hardtke, C.S. (2000).  Vascular continuity and auxin signals.. Trends in Plant Sciences. 5, 387-393.
Berleth, T., Mattsson, J., Hardtke, C.S. (2000).  Vascular Continuity, Cell Axialization and Auxin.. Plant Growth Regulation. 32, 173-185.
1999
Leyser, O., Berleth, T. (1999).  A molecular basis for auxin action.. Seminars in Cell & Developmental Biology. 10, 131-137.
Mattsson, J., Sung, R.Z., Berleth, T. (1999).  Responses of plant vascular systems to auxin transport inhibition.. Development. 126, 2979-2991.
1998
Hardtke, C.S., Berleth, T. (1998).  The Arabidopsis gene monopteros encodes a transcription factor mediating embryo axis formation and vascular development.. EMBO J.. 17(5), 1405-1411.
Berleth, T. (1998).  Experimental approaches to Arabidopsis embryogenesis.. Plant Physiol. Biochem.. 36 (1-2), 69-82.
1996
Hardtke, C.S., Muller, J., Berleth, T. (1996).  Genetic similarity among Arabidopsis thaliana ecotypes estimated by DNA sequence comparison.. Plant Molecular Biology. 32(5), 915-922.
Przemeck, G.K.H., Mattsson, J., Hardtke, C.S., Sung, Z.R., Berleth, T. (1996).  Studies on the role of the Arabidopsis gene MONOPTEROS in vascular development and plant cell axialization.. Planta. 200, 229-237.
Berleth, T., Hardtke, C.S., Przemeck, G.K.H., Muller, J. (1996).  Mutational analysis of root initiation in Arabidopsis.. Plant and Soil. 187, 01 .
Hardtke, C.S., Berleth, T. (1996).  Genetic and contig map of a 2200 kb region encompassing 5.5 cM on chromosome 1 of Arabidopsis thaliana.. Genome. 39(6), 1086-1092.
1994
Jurgens, G., Torres Ruiz, R.A., Laux, T., Mayer, U., Berleth, T. (1994).  Early events in apical-basal pattern formation in Arabidopsis.. Molecular-Genetic Analysis of Plant Metabolism and Development.
Jurgens, G., Torres Ruiz, R.A., Berleth, T. (1994).  Embryonic pattern formation in flowering plants.. Annu. Rev. Genet.. 28, 351-371.
1993
Berleth, T., Jurgens, G. (1993).  The role of the monopteros gene in organising basal development in the Arabidopsis embryo.. Development. 118(2), 575-587.
In Press
Scheres, B., Berleth, T. (0).  Root development: new meaning for root canals?. Curr. Opin. in Plant Biol.. 1, 32-36.